Study: #Chemotherapy Can Fuel Growth Of #BreastCancer #Tumors

allaboutbreasthealth,com

In 23% of cell lines, chemotherapy causes the cancer to spread, become more resistant and less likely to “cure,” cures which is what chemotherapy pitches as the goal of undergoing the harsh treatments. Russian

scientists found that a neoadjunvant chemotherapy in patients with breast cancer can stimulate the growth of a tumor. Nicholay Litvyakov, D.Sc. at Cancer Research Institute, Head of the Tumor Virology Laboratory, and TSU researcher Marina Ibragimova, were published with these results in Siberian Journal of Oncology. The scientist used breast cancer biopsies in the study. Results of the study were published on MedicalXpress.com. 

The researchers concluded that under the influence of chemotherapy, it is possible to stimulate the evolution of a resistant tumor that does not respond to the effects of chemotherapy.

TSU scientists have found that chemotherapy fully or partially destroyed the tumor clones in the majority of patients, but 23 percent of women surveyed showed new tumor formation under the influence of NHT. Some chromosomes or partial chromosomes doubled in these clones, and the tumor cells became more resistant. This phenomenon is called amplification, and is a negative consequence of chemotherapy—almost all of these patients developed metastases, while the remaining patients had no metastases in the five-year period of observation.

The researchers concluded that under the influence of chemotherapy, it is possible to stimulate the evolution of a resistant tumor that does not respond to the effects of chemotherapy.

“We have preliminary results indicating that chemotherapy may cause the appearance of mutations which had not been observed before in the form of amplifications of chromosomal regions. In some cases it was a reason for occurrence of hematogenous metastasis,” says Ibragimova. “We should find out the causes and methods for anticipating tumor development. Thus there is no doubt that chemotherapy shall have strictly personalized character, depending on the properties of tumor and patient.”

23% is an excessively high number of people and this study should warrant much further, much more involved research, not just in Russia, but here in the states. Unfortunately pharmaceutical companies and makers of chemotherapy drugs aren’t going to be all too helpful in such endeavors. The Russian researchers are attempting to learn if they can distinguish between tumor cells and how they would be effected by these treatments. We need much more of this type of research to be conducted. Chemotherapy is a harsh treatment that has long been suspected of causing further cancers throughout the body. It destroys good cells without distinction and is attached to harsh side effects.