Fennel For Painful Periods: A Clinically Proven Drug Alternative

Posted on: Monday, October 30th 2023 at 7:30 am
Written By: Sayer Ji, Founder

Painful periods (primary dysmenorrhea) afflict approximately 25% of all women, with estimates for adolescents reaching as high as 90%.[i]  Given the prevalence of this disabling condition, and that treatment usually involves NSAID drugs and sometimes oral contraceptives - both of which have serious, even life-threatening side effects - natural alternatives are desperately needed.  So what better place to look than your spice rack, which an under reported body of clinical research indicates may offer solutions at least as effective as drugs.

There are no less than three clinical studies in the medical literature comparing fennel to the NSAID drug mefenamic acid for the treatment of painful periods in women.

The first, which occurred in 2002, randomized two groups of 55 high-school girls (mean age 13) to receive either fennel seed extract or mefenamic acid for 2 months. The remarkable results showing the superiority of fennel were reported as follows:

"In the fennel group, 80% of girls and in the mefenamic acid group, 73% of girls showed complete pain relief or pain decrease, while 80% in the fennel group and 62% in the mefenamic acid group no longer needed to rest. There was no significant difference between the 2 groups in the level of pain relief."

The next study, published in 2003, took 60 girls (mean age 12.5) with primary dysmenorrhea, administering either either 25 drops of 2% essence of fennel seed extract (taken every 4 hours) or 250 mg (taken every 6 hours) of mefenamic acid over the course of their menstrual cycle. 

They reported their results as follows:

"The essence of fennel can be used as a safe and effective herbal drug for primary dysmenorrhea, however, it may have a lower potency than mefenamic acid in the dosages used for this study." [Note: "No complication was reported in mefenamic acid treated cycles, but five cases (16.6%) withdrew from the study due to fennel's odor and one case (3.11%) reported a mild increase in the amount of her menstrual flow."]

A third study, published this year in the Iranian Journal of Nursery and Midwifery, which as an open access article can be read in its entirety here, describes the results of a randomized parallel-group clinical trial, comparing the effects of 2% fennel extract drops to mefenamic acid (cap 250 mg) in the management of primary dysmenorrhea in 60 18-25 year olds.

The results of the study were reported as follows:

"The present study showed that the efficacy of fennel drop 2% in pain relief in primary dysmenorrhea is comparable to the efficacy of common NSAIDs such as mefenamic acid cap. Investigators recommend that another product of fennel such as tab, cap, or fennel oil might be more acceptable than the essence. One subject had severe menstruation after taking fennel drop."

It should be emphasized that many herbs, and especially their seeds, are very powerful and should be treated with great respect, consideration and care. Because fennel is antispasmodic and causes muscular relaxation, it can significantly increase the risk of menstrual bleeding. Anyone with a history of excessive bleeding would need to be especially cautious, and certainly, anyone wishing to dabble in herbalism would be well advised to seek the guidance of a licensed medical herbalist and/or integrative medical practitioner. 

For additional research on the potential health benefits of fennel, view our Fennel Research page. For additional research on painful periods, view our Dysmenorrhea Research page.

References [i] eMedicine > Dysmenorrhea By Andre Holder, Laurel D Edmundson and Mert Erogul. Updated: Dec 31, 2009   Originally Published November 23, 2013.